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Tumor metabolic reprogramming has emerged as a hallmark of cancer, and among various metabolic pathways, lysophosphatidic acid (LPA)a bioactive lipid mediatorhas been increasingly implicated in PCa progression, particularly CRPC transformation

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For immunohistochemical staining, the tissue sections were inactivated by endogenous peroxidase with 3% hydrogen peroxide for 10 min and blocked with goat serum for 30 min

Causes of high vitamin B12 The causes fall into two broad categories: exogenous (something youre taking in) and endogenous (something happening inside your body)

Definitions: microplastics, BPA, PM2.5, phthalates, and more [6:30]